Search on: MONOMERIC GTP-BINDING PROTEINS 
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Descriptor English:   Monomeric GTP-Binding Proteins 
Descriptor Spanish:   Proteínas de Unión al GTP Monoméricas 
Descriptor Portuguese:   Proteínas Monoméricas de Ligação ao GTP 
Synonyms English:   ras-Related GTPases
G-Proteins, Monomeric
GTP-Binding Proteins, Monomeric
Monomeric G-Proteins
Small G-Proteins
Small GTPases  
Tree Number:   D08.811.277.040.330.300.400
D12.644.360.525
D12.776.157.325.515
D12.776.476.525
Definition English:   A class of monomeric, low molecular weight (20-25 kDa) GTP-binding proteins that regulate a variety of intracellular processes. The GTP bound form of the protein is active and limited by its inherent GTPase activity, which is controlled by an array of GTPase activators, GDP dissociation inhibitors, and guanine nucleotide exchange factors. This enzyme was formerly listed as EC 3.6.1.47 
History Note English:   2000 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   34413 
Unique Identifier:   D020559 

Occurrence in VHL:
 

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